Stephen Doster

  • An inward look into Biochemistry

    An inward look into Biochemistry

    By Wendy Bindeman Welcome to the first of four articles in our new “Meet the Departments” series! The Vanderbilt University School of Medicine Basic Sciences is composed of four departments: Biochemistry, Cell and Developmental Biology, Molecular Physiology and Biophysics, and Pharmacology. Through this article series, we… Read More

    Jan. 6, 2022

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    Study explores how bacteria become drug resistant

    Researchers at Vanderbilt University and the University of Arizona have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs. Their findings, which were reported recently in the journal Nature Chemical Biology, will aid the search for inhibitors… Read More

    Jan. 6, 2022

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    Vanderbilt extends its longest ongoing drug discovery agreement with pharmaceutical company through 2023

    Vanderbilt has extended its longest ongoing drug discovery agreement with Osaka, Japan-based Ono Pharmaceutical Co., Ltd., a research and development-oriented pharmaceutical company that is committed to creating innovative medicines in specific areas, through November 2023. The initial agreement was signed in November… Read More

    Dec. 22, 2021

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    Study sets framework for precision surveillance of colorectal cancer

    by Tom Wilemon A team of Vanderbilt researchers has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine. Their study, published Dec. 14 in Cell, describes findings from a single-cell transcriptomic and imaging atlas… Read More

    Dec. 17, 2021

  • On a dark green background, several short pieces of DNA “float” around. One is vertical on the left side of the image, and a zoomed-in portion is seen horizonally on the right. The DNA on its side has more details (it’s a stick model) and shows water molecules (also stick models) surrounding the DNA. Hydrogen bonds between the water and the DNA are visualized as yellow dashes.

    Neutrons take a deep dive into water networks surrounding DNA

    By Olivia Trani This article was originally published on the Oak Ridge National Laboratory website and was adapted with permission for publication at Vanderbilt University. Water plays several important roles within the human body, even affecting the DNA in our cells. The entire surface of a DNA… Read More

    Dec. 17, 2021

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    Producing green fuel, and more rapid determination of the biological consequences of gene editing

    A team of Vanderbilt researchers led by Jamey Young, Cornelius Vanderbilt Professor of Engineering,  John McLean, department chair and Stevenson Professor of Chemistry, and Carl Johnson, Cornelius Vanderbilt Professor of Biological Sciences, has described a novel method for rapidly characterizing… Read More

    Dec. 15, 2021

  • Dr. James Crowe Jr., professor of medicine, in his lab at Medical Research Building IV. Dr. Crowe is the subject of a feature article in the upcoming Winter 2018 issue of Vanderbilt Magazine. Crowe, who is the Ann Scott Carell Professor of Pediatrics, Pathology, Microbiology and Immunology, as well as director of the Vanderbilt Vaccine Center, has spent his career hunting for a universal flu vaccine. He has re-engineered how flu vaccines work and is on the edge of creating a single shot that covers all flu strains. In a new initiative announced in October, he will lead an international team of researchers as they launch clinical trials of his new vaccine.(John Russell/Vanderbilt University)

    Antibodies discovered at Vanderbilt for prevention of COVID-19 granted FDA emergency use authorization

    On Wednesday, the U.S. Food and Drug Administration granted emergency use authorization (EUA) to the global biopharmaceutical company AstraZeneca for a long-acting antibody combination which  protects against COVID-19, discovered last year at Vanderbilt University Medical Center (VUMC). A number of medical conditions result in immune compromise, from treatments for many cancers… Read More

    Dec. 9, 2021

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    McLean elected as 2021 National Academy of Inventors Fellow

    John McLean, Stevenson Professor of Chemistry, Stevenson Chair and the director of the Center for Innovative Technologies, has been elected a 2021 Fellow of the National Academy of Inventors… Read More

    Dec. 8, 2021

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    A potential new approach for the treatment of schizophrenia

    THE IDEA   Jeffrey Conn (John Russell/Vanderbilt University) James Maksymetz A new study led by Jeff Conn, Lee E. Limbird Chair in Pharmacology, James Maksymetz, a former graduate student in the Conn laboratory, and other collaborators at the Warren Center for… Read More

    Dec. 8, 2021

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    Deciphering the Circuits in Neuroscience Research

    Around 500 million people around the world are affected by poor mental health including disorders such as depression, schizophrenia, bipolar disease and dementia with a significant impact on quality of life as well as associated social and economic consequences.1 Boehringer Ingelheim is dedicated to redefining the management of mental health. Read More

    Dec. 7, 2021