Stephen Doster

by Marissa Shapiro Jan. 27, 2021, 9:00 AM For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumors in days.  The article, “MYC regulates ribosome… Read More

Jan. 21, 2021, 11:00 AM by Leigh MacMillan Brain inflammation plays a role in human epilepsy, but most studies have focused on acquired epilepsies, such as those due to head trauma, viral infection or other insults. Neuroinflammation has never been reported in genetic epilepsy associated with ion channel gene mutations. … Read More

by Marissa Shapiro Jan. 26, 2021, 9:00 AM A chemical probe molecule—a “first gen” molecule that can be used for drug development—that targets a host cell’s protein quality control pathways can dramatically reduce infection by Dengue and Zika viruses. The research led by Lars… Read More

Jan. 21, 2021, 10:00 AM by Sarah Glass WDR5 is a protein that is overexpressed in a variety of cancers. Inhibiting WDR5 by targeting the WDR5-interaction (WIN) site can inhibit the growth of cancer cells in vitro, but this mechanism of action has not been fully elucidated.  Publishing in … Read More

by Marissa Shapiro Jan. 12, 2021, 9:00 AM Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects one in 10 Americans. Wenbiao… Read More

by Marissa Shapiro Jan. 11, 2021, 9:00 AM Borden Lacy (Vanderbilt University) Borden Lacy, Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology, has been named director of the Vanderbilt Center for Structural Biology.  She… Read More

by Marissa Shapiro Jan. 8, 2021, 9:06 AM Vanderbilt alumnus Graham Gaylor and Assistant Professor of Pharmacology Cody Siciliano have been selected for the 2021 Forbes “30 Under 30.” The 10th annual list recognizes 600 entrepreneurs, scientists, activists and entertainers changing the world. Graham… Read More

Jan. 6, 2021, 10:31 AM by Bill Snyder Researchers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and Vanderbilt University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated… Read More

by Marissa Shapiro Dec. 18, 2020, 11:55 AM Work on COVID-19 theraputics at Vanderbilt University Medical Center (VUMC) As the United States and the rest of the world witness the rollout of new vaccines targeting COVID-19—as well as better treatment options to fight the… Read More

Dec. 17, 2020, 10:05 AM Ann Richmond, MD, Chi Yan, PhD, Jinming Yang, PhD, and colleagues are studying ways to boost antitumor immunity and reduce tumor growth in breast cancer and melanoma. (photo by Donn Jones) by Leigh MacMillan A team of Vanderbilt investigators has discovered that blocking a certain… Read More