Lorena Infante Lara
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2024 Call for Applications – Stanley Cohen Innovation Fund
The Vanderbilt University School of Medicine Basic Sciences is soliciting 2024 applications for research awards from the Stanley Cohen Innovation Fund. The Cohen fund supports high-risk, ground-breaking research with the potential to open new fields of scientific inquiry and biomedical impact. Read MoreJul. 16, 2024
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Vanderbilt scientists develop new tool that could lead to noninvasive “liquid biopsies”
Researchers from the School of Medicine Basic Sciences recently developed an analytical tool called EV Fingerprinting that could lead to the use of “liquid biopsies” as a substitute for traditional biopsies for certain patients or diseases. Read MoreJul. 15, 2024
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Basic Sciences celebrates its 2023–24 Russell G. Hamilton Graduate Leadership Institute awardees
The Russell G. Hamilton Graduate Leadership Institute, an initiative from the Vanderbilt University Graduate School, recognized over 130 students from the School of Medicine Basic Sciences with awards during the 2023–24 academic year. Read MoreJun. 21, 2024
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New drug candidates targeting blood clots developed through computer-aided drug design
Using computer-aided drug design, the labs of Heidi Hamm, Jens Meiler, and Craig Lindsley generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read MoreJun. 6, 2024
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New cancer target could push new drugs into the clinic
New work by Professor of Cell and Developmental Biology Bill Tansey and colleagues has determined that a new type of inhibitor—a WINi—targets cancer cells in a novel way and suggests exploiting this pathway in future anticancer drug development efforts. Read MoreMay. 14, 2024
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Research Snapshot: Exploring the range of AlphaFold2’s utility within the realm of protein dynamics
Benjamin P. Brown, assistant professor of pharmacology, and colleagues in the departments of molecular physiology and biophysics, pharmacology, and chemistry, have determined that AlphaFold2 can be used to generate approximations of relative conformational preferences of proteins, which will help researchers better understand a protein’s structure and function across a range of conditions and mutational states. Read MoreMay. 9, 2024
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Lau lab publishes authoritative reference article on the hallmarks of precancer
Ken Lau, professor of cell and developmental biology, and colleagues have laid out the principles governing the biology of early, precancerous lesions, which are different from the principles that govern cancers. Their authoritative perspective was published in Cancer Discovery in April 2024. Read MoreMay. 7, 2024
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Hodges lab sheds new light on mechanisms of gene regulatory divergence between species
The labs of Emily Hodges, assistant professor of biochemistry, and Tony Capra, associate professor of epidemiology and biostatistics at the University of California, San Francisco, have devised a method to separate the relative contributions of cis vs. trans regulatory mechanisms to gene regulatory divergence between species. Read MoreApr. 18, 2024
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Nguyen marries basic and translational approaches to ID new brain region responsible for epileptic seizures
Assistant professor of pharmacology Quynh Anh Nguyen spearheaded research that points to a previously unidentified region of the hippocampus as responsible for epileptic seizures. The work could lead to new avenues of treatment to help epilepsy patients control their seizures. Read MoreApr. 17, 2024
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New structures offer insight into how a bacterial motor powers bacterial chemotaxis, a key infectious process
An international collaboration led by Professor of Pharmacology Tina Iverson identified how bacteria move in response to their environment, a process essential for infection by pathogens. Read MoreApr. 17, 2024