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Research led by Dylan Burnette, associate professor of cell and developmental biology, and first-author Abigail Neininger, a graduate student in the Burnette lab, identified the Hippo pathway as a key regulator of heart muscle cell division, which has large translational implications for treatments after a heart attack. Their article was… Read More

A Vanderbilt University Medical Center licensee, Evotec SE, announced on January 28, 2020 that EVT894, a monoclonal antibody to treat and potentially prevent chikungunya virus infections, has entered clinical development. The Phase I, randomised, double-blind, single centre, single dose escalation study to evaluate the safety, pharmacokinetics, and immunogenicity of EVT894 vs… Read More

by Marissa Shapiro Dec. 18, 2020, 11:55 AM Work on COVID-19 theraputics at Vanderbilt University Medical Center (VUMC) As the United States and the rest of the world witness the rollout of new vaccines targeting COVID-19—as well as better treatment options to fight the… Read More

REQUEST FOR APPLICATIONS Rare Genetic Diseases Opening January 2021 Rolling Submission-Review Ancora Innovations is a collaboration between Vanderbilt University and Deerfield Management, focused on the union of Vanderbilt’s innovative life science discovery efforts and Deerfield’s commitment to accelerating state-of-the-art drug development. Deerfield will fund Ancora Innovation with up to $65… Read More

By Alexandra Fuller By the time March rolls around, New Year’s resolutions to ditch the expensive lattes and spend less time (and money) shopping online are often far behind us. Activity within the nucleus accumbens, a region of the brain implicated in motivation and addiction, may be at play. Read More

by Marissa Shapiro Nov. 17, 2020, 12:00 PM Ancora Innovation LLC, a Deerfield Management company that supports Vanderbilt University’s innovative life science research, will fund further research into therapeutics for Charcot-Marie-Tooth disease, an inherited condition that damages peripheral nerves. This is the third Vanderbilt project… Read More

By Naotoshi Nakamura Dr. Nakamura, a Specially Appointed Associate Professor at the Center for Mathematical Modeling and Data Science, Osaka University, was a visiting scholar in the Vito Quaranta lab and has since become a long-distance participant in discussions and lab meetings. Nakamura has also been appointed as… Read More

By Sara Eaton There are biological differences in how male and female mice respond to different cues in their environment. Deciphering those differences can help researchers develop drugs that work equally well in both human sexes. New research from the labs of Erin Calipari and Cody Siciliano, both… Read More

By Heather Caslin Approximately 30 million Americans have type 2 diabetes. The majority are over 45 years old. © Vitalii Vodolazskyi, stock.adobe.com Within the pancreas, β-cells produce insulin that delivers energy to tissues through glucose. People with type 2 diabetes have smaller, less functional β-cells; however, the mechanisms that drive… Read More

by Ryan Underwood Jun. 16, 2020, 4:23 PM Vanderbilt University’s Warren Center for Neuroscience Drug Discovery has entered into an exclusive worldwide licensing and collaboration agreement with San Diego-based ACADIA Pharmaceuticals Inc., which will seek to develop and commercialize treatments for central… Read More