Cryo- EM

An international collaboration led by Professor of Pharmacology Tina Iverson identified how bacteria move in response to their environment, a process essential for infection by pathogens. Read More

The 2024 Center for Structural Biology Symposium, which took place on March 28, celebrated its decades of success, research undertakings, and goal of strengthening the structural biology community at Vanderbilt. Read More

Brandt Eichman and Walter Chazin, professors of biochemistry, worked together to provide a better understanding of how exactly DNA replication is initiated. Their work will influence novel small molecule modifier designs that may serve as tools for detailed studies of DNA replication in cells and eventual therapies. Read More

Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory. Read More

Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read More

Research led by co-first authors Emily Schmitz, a graduate student in the Chemical and Physical Biology program, and Hirohide Takahashi, a research instructor in molecular physiology and biophysics, identified the structure of the human type-3 inositol 1,4,5-triphosphate, or IP3, receptor in several conformations using cryo-electron microscopy. Schmitz and Takahasi, who… Read More

The Office of the Dean of Basic Sciences is pleased to announce the recipients of the 2022 Vanderbilt School of Medicine Basic Sciences Core Development Grants, which provide each awardee with up to $50K toward the purchase of capital equipment, the development of a new core technology or service, or… Read More