‘insulin’
CRISPR screen identifies role for a specific protein in insulin secretion
Jan. 25, 2023—By Leah Mann The labs of Wenbiao Chen, associate professor of molecular physiology and biophysics, and Irina Kaverina, professor of cell and development biology, recently published a study in Molecular Metabolism focused on detecting genes that regulate insulin secretion. The authors demonstrated a new role for the Commander complex—a bound group of 16 proteins—in insulin...
Improving insulin sensitivity
Mar. 15, 2022—By Wendy Bindeman Ambra Pozzi, professor of medicine and of molecular physiology and biophysics, first author Kakali Ghoshal (a postdoc in the Pozzi lab), and colleagues recently published a study showing that supplementation with an analog of a lipid metabolite called epoxyeicosatrienoic acid, which is involved in insulin signaling, reverses insulin resistance in the livers...