Pharmacology

Vanderbilt investigators have revealed the mechanisms by which the chemokine receptor CXCR2, is associated with melanoma tumor formation and growth — a discovery that supports the continued development of drugs that inhibit the receptor’s activity. Ann Richmond, PhD, Ingram Professor of Cancer Biology and professor of Pharmacology, is internationally known… Read More

Vanderbilt investigators have revealed the mechanisms by which the chemokine receptor CXCR2, is associated with melanoma tumor formation and growth — a discovery that supports the continued development of drugs that inhibit the receptor’s activity. Ann Richmond, PhD, Ingram Professor of Cancer Biology and professor of Pharmacology, is internationally known… Read More

Atrial fibrillation (A-fib) — the most common cardiac arrhythmia (irregular heartbeat) — is associated with increased risk of stroke, heart failure, dementia and death. Antiarrhythmic drug therapy to prevent A-fib has remained elusive. The strongest genetic risk factors for A-fib in humans are variants in a chromosomal region including the gene… Read More

Jackson Roberts II, MD, an internationally known clinical pharmacologist in the Vanderbilt University School of Medicine who helped define the role of lipid peroxidation and oxidative stress in human disease, died May 31 in Nashville. He was 79. Dr. Roberts, professor of Pharmacology and Medicine, emeritus, was perhaps best known… Read More

Craig W. Lindsley, University Distinguished Professor of Pharmacology, Biochemistry and Chemistry, who holds the William K. Warren, Jr. Chair in Medicine, was recently announced as a 2022 fellow of the American Society for Pharmacology and Experimental Therapeutics for his demonstrated excellence and… Read More

By Leah Mann Graduate student Sarah Kurley with thesis advisor Al Reynolds. (Photo by Mary Donaldson) Albert “Al” Reynolds, celebrated and respected professor of pharmacology, emeritus, passed away earlier in November. He had retired in August after 26 years at Vanderbilt University. In the nearly three decades of Reynolds’ affiliation… Read More

The growth of epithelial ovarian cancer, one of the most lethal malignancies, is associated with the presence of tumor-associated macrophages (TAMs), white blood cells that can block the anti-cancer activity of the immune system and immunotherapy. Fortunately, TAMs can be “repolarized,” converted from immunosuppressive tumor-promoters to inflammatory tumor-fighters. Now,… Read More

Heidi Hamm, Yun Young Yim By Emily Overway Researchers in the lab of Heidi Hamm, a professor of pharmacology who also holds the Aileen M. Lange and Annie Mary Lyle Chair in Cardiovascular Research, recently published a paper exploring the G protein subunits that interact with the SNARE complex. The… Read More

L-R: Ann Richmond, Chi Yan By Wendy Bindeman Ann Richmond, professor of pharmacology, and Chi Yan, a research assistant professor in the Richmond lab, recently published a study showing that expression of a protein called CD40 can be used to predict response to immunotherapy in malignant melanoma. Read More

Richard Sando, assistant professor of pharmacology, has been selected to receive a 2022 Sloan Research Fellowship, one of the most competitive and prestigious awards available to early-career researchers. The fellowships, awarded annually by the Alfred P. Sloan Foundation, honor extraordinary U.S. and Canadian scientists and scholars… Read More