School Of Medicine Basic Sciences

A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. Read More

Congratulations to our School of Medicine Basic Sciences members who were promoted or received new appointments from July to September 2024. These individuals significantly enrich our pursuit of pathbreaking research and contribute to the growth and success of our school.  Read More

Mirazul Islam, a graduate student in the lab of Professor Ken Lau, has developed a molecular clock that records the timing of cellular events at a single-cell resolution. Read More

Charles Darwin, serenely composed in anticipation of the Voyage of the Beagle. The intrepid CEO of The Protein Society, Raluca Cadar, again used her special Carpathian “connections” to set up our Annual TPS Halloween interview, this year with none other than Charles Darwin.  We listen in on his conversation with… Read More

Sloan Kettering Institute’s PaineWebber Professor of Cancer Genetics Agnel Sfeir will present the Vanderbilt School of Medicine Basic Sciences Apex Lecture on Oct. 30, 2024. Read More

Led by Craig W. Lindsley, Vanderbilt drug discovery experts set out to develop a backup drug candidate to improve memory loss in people with Alzheimer’s disease. Read More

Calipari wins award for transforming scientists’ understanding of how behavioral circuits are dysregulated by long-term drug use and for her commitment to train and support the next generation of addiction scientists. Read More

Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, proposed and validated a mechanism that solved a decades-old mystery: he shed light on the process by which epithelial cells, polarized cells that face the outside world, sort and deliver the specialized proteins they need at each cell’s poles. Read More

A research grant to study lung and cerebral organoids will yield insights into the sensitivity of lung and brain tumors to commercially available antibody-drug conjugate payloads. The OVPRI Industry Collaborations group facilitated the collaboration. Read More

By Chuck Sanders When I was 13, my brother Scott (12) and I joined our neighbors Matha (12) and Jay (10) on a trip to their family cottage on the bank of the Allegheny River in western Pennsylvania. I had fantasized about this trip for months; I… Read More