‘Wente’
Cell-to-cell variability in gene expression is regulated by casein kinase II
May. 9, 2014—Casein kinase II Regulation of the Hot1 Transcription Factor Promotes Stochastic Gene Expression Laura T. Burns and Susan R. Wente Capsule Background: Dynamic signaling events are required for cell-to-cell gene expression differences during responses to environmental stress. Results: During hyperosmotic stress, casein kinase II (CK2) interacts with and phosphorylates the Hot1 transcription factor. Conclusion:...