Discoveries

Cannabis is well-known for having an effect on eating behaviors. However, how the natural cannabinoid molecules found in the body regulate feeding and eating is not well researched. Masoud Ghamari-Langroudi, research assistant professor of molecular physiology and biophysics, research assistant professor of pharmacology and faculty affiliate… Read More

The American Association for Cancer Research (AACR) has inducted Jennifer Pietenpol, PhD, and Yu Shyr, PhD, into the 2022 class of Fellows of the AACR Academy. The mission of the AACR Academy is to recognize and honor distinguished scientists whose scientific contributions have propelled significant innovation and progress against cancer. Read More

By Wendy Bindeman Ambra Pozzi Ambra Pozzi, professor of medicine and of molecular physiology and biophysics, first author Kakali Ghoshal (a postdoc in the Pozzi lab), and colleagues recently published a study showing that supplementation with an analog of a lipid metabolite called epoxyeicosatrienoic acid, which is involved in insulin… Read More

Heidi Hamm, Yun Young Yim By Emily Overway Researchers in the lab of Heidi Hamm, a professor of pharmacology who also holds the Aileen M. Lange and Annie Mary Lyle Chair in Cardiovascular Research, recently published a paper exploring the G protein subunits that interact with the SNARE complex. The… Read More

L-R: Ann Richmond, Chi Yan By Wendy Bindeman Ann Richmond, professor of pharmacology, and Chi Yan, a research assistant professor in the Richmond lab, recently published a study showing that expression of a protein called CD40 can be used to predict response to immunotherapy in malignant melanoma. Read More

By Aaron Conley Stanley Cohen and Vanderbilt Chancellor Joe Wyatt (1986). Houra Merrikh, professor of biochemistry, and Teru Nakagawa, associate professor of molecular physiology and biophysics, have both been selected to receive one-year research awards from the Stanley Cohen Innovation Fund. The awards will support groundbreaking and… Read More

By Sohini Roy People with type 1 diabetes generate little to no insulin, which promotes the absorption of glucose from the blood. The transcriptional coregulator Swi-independent 3 — or Sin3 — switches on and off the genes that drive crucial biological processes during prenatal development, including cellular differentiation, maturation, survival, metabolism,… Read More

By Natalya Ortolano Myosin motors and long actin filaments accumulate at the center of dividing cells to constrict the membrane. When a bouncy ball deforms under the weight of your body, its rubber membrane stretches and contracts. Likewise, the membrane of a cell doubling itself prior to division must accommodate… Read More

By Brad Davidson VIR-CLASP has the potential to find new therapeutic targets during infection by a wide variety of RNA viruses. RNA viruses invade cells and co-opt cellular machinery to replicate and translate their genomic material. To stave off infection until immune cells arrive, host cells rely on “intrinsic immunity… Read More

By Mary Alice Keller Triple-negative breast cancer is a type of breast cancer that tests negative for the three receptors that are commonly found in breast cancer: estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2) receptors. The oncogene MYCN regulates cancer cell growth, proliferation, metabolism, and… Read More