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Melanoma treatment response
Although targeted therapies have been developed for melanoma patients, tumor progression eventually results. Understanding characteristics of melanoma associated with treatment resistance is important for prolonging therapy effectiveness. In a retrospective study of patients treated with BRAF and/or MEK inhibitors, Chi Yan, PhD, Ann Richmond, PhD, and… Read MoreFeb. 25, 2022
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Monteggia appointed co-editor for Neuropsychopharmacology
By Aaron Conley Lisa Monteggia, Ph.D. Barlow Family Director of the Vanderbilt Brain Institute and acclaimed neuroscientist Lisa Monteggia was named incoming co-principal editor, along with Dr. Tony George from the University of Toronto, of the journal Neuropsychopharmacology. Their appointments begin… Read MoreFeb. 8, 2022
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New Awards Announced for Postdoctoral Scholars in Biochemistry
By Dave Cortez and Aaron Conley The Department of Biochemistry at Vanderbilt University School of Medicine Basic Sciences announced new annual awards for postdoctoral scholars called the Destination Biochemistry Postdoctoral Scholar Awards. These awards will support exceptional postdoctoral fellows from around the world as they join labs in the Department… Read MoreJan. 10, 2022
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An inward look into Biochemistry
By Wendy Bindeman Welcome to the first of four articles in our new “Meet the Departments” series! The Vanderbilt University School of Medicine Basic Sciences is composed of four departments: Biochemistry, Cell and Developmental Biology, Molecular Physiology and Biophysics, and Pharmacology. Through this article series, we… Read MoreJan. 6, 2022
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In memory of Zach Jones
By Mariana Byndloss If I could define Zach in one word, it would be LIGHT. Zach brought LIGHT to the world around him with his kindness, open mind and his way of accepting others and always seeing the good in people. And the funniest thing about it is that… Read MoreSep. 24, 2021
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Discovery of a pathway that regulates heart muscle regeneration
Research led by Dylan Burnette, associate professor of cell and developmental biology, and first-author Abigail Neininger, a graduate student in the Burnette lab, identified the Hippo pathway as a key regulator of heart muscle cell division, which has large translational implications for treatments after a heart attack. Their article was… Read MoreSep. 9, 2021
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Evotec begins Phase I clinical trial of chikungunya antibody discovered by James Crowe, MD and VUMC colleagues
A Vanderbilt University Medical Center licensee, Evotec SE, announced on January 28, 2020 that EVT894, a monoclonal antibody to treat and potentially prevent chikungunya virus infections, has entered clinical development. The Phase I, randomised, double-blind, single centre, single dose escalation study to evaluate the safety, pharmacokinetics, and immunogenicity of EVT894 vs… Read MoreFeb. 5, 2021
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ANCORA INNOVATIONS – Vanderbilt University | Deerfield
REQUEST FOR APPLICATIONS Rare Genetic Diseases Opening January 2021 Rolling Submission-Review Ancora Innovations is a collaboration between Vanderbilt University and Deerfield Management, focused on the union of Vanderbilt’s innovative life science discovery efforts and Deerfield’s commitment to accelerating state-of-the-art drug development. Deerfield will fund Ancora Innovation with up to $65… Read MoreDec. 17, 2020
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Medium spiny neurons and “sticking” to bad habits
By Alexandra Fuller By the time March rolls around, New Year’s resolutions to ditch the expensive lattes and spend less time (and money) shopping online are often far behind us. Activity within the nucleus accumbens, a region of the brain implicated in motivation and addiction, may be at play. Read MoreDec. 15, 2020
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A visiting scholar’s experience with the lockdown in Nashville
By Naotoshi Nakamura Dr. Nakamura, a Specially Appointed Associate Professor at the Center for Mathematical Modeling and Data Science, Osaka University, was a visiting scholar in the Vito Quaranta lab and has since become a long-distance participant in discussions and lab meetings. Nakamura has also been appointed as… Read MoreOct. 7, 2020