Hassane Mchaourab
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Expert in bio-inspired AI systems visits Vanderbilt to discuss the future potential of neuromorphic supercomputers
At a recent Center for Applied AI in Protein Dynamics seminar, Christian Mayr of Technische Universität Dresden discussed how new hardware technologies will transform AI development and allow machines to mimic the efficiency and processing power of the human brain. Read MoreAug. 26, 2024
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Research Snapshot: Exploring the range of AlphaFold2’s utility within the realm of protein dynamics
Benjamin P. Brown, assistant professor of pharmacology, and colleagues in the departments of molecular physiology and biophysics, pharmacology, and chemistry, have determined that AlphaFold2 can be used to generate approximations of relative conformational preferences of proteins, which will help researchers better understand a protein’s structure and function across a range of conditions and mutational states. Read MoreMay. 9, 2024
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Vanderbilt launches Center for Applied Artificial Intelligence in Protein Dynamics
The School of Medicine Basic Sciences has launched the Center for Applied Artificial Intelligence in Protein Dynamics, which is focused on the intersection of artificial intelligence, machine learning, and macromolecular mechanism. It is helmed by Hassane Mchaourab, who holds the Louise B. McGavock Chair in the Department of Molecular Physiology and Biophysics. Read MoreMar. 7, 2024
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Apex Lecture presented by renowned AlphaFold founder
The Aug. 30 School of Medicine Basic Sciences Apex Lecture featured visionary biophysicist John Jumper (BS’07). His talk described AlphaFold, the revolutionary protein structure-predicting program, that he co-developed. Read MoreSep. 13, 2023
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John Jumper, developer of AlphaFold, to present an Apex Lecture on August 30
John Jumper, Ph.D. To highlight major inflection points in research, the Vanderbilt School of Medicine Basic Sciences launched the Apex Lecture Series earlier this year, which allows the Basic Sciences community to engage with researchers from around the world who are influencing the trajectory of their fields. John… Read MoreAug. 8, 2023
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Vanderbilt launches Center for Applied Artificial Intelligence in Protein Dynamics
Vanderbilt University School of Medicine Basic Sciences has launched the Center for Applied Artificial Intelligence in Protein Dynamics, which is focused on the intersection of artificial intelligence, machine learning and macromolecular mechanism. It will be led by Hassane Mchaourab, who holds the Louise B. McGavock Chair… Read MoreApr. 12, 2023
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Collaborative research yields new protein structure
Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read MoreMay. 16, 2022
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First-time isolation of Glucose-6-phosphatase leads to novel discoveries
Researchers from the labs of Hassane Mchaourab and Richard O’Brien, both professors of molecular physiology and biophysics, have successfully isolated active glucose-6-phosphatase (G6Pase) and characterized its biophysical and biochemical properties. G6Pase dysfunction is a primary contributor to metabolic diseases, including diabetes, and labs have been trying for years to isolate… Read MoreJan. 25, 2022
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Study explores how bacteria become drug resistant
Researchers at Vanderbilt University and the University of Arizona have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs. Their findings, which were reported recently in the journal Nature Chemical Biology, will aid the search for inhibitors… Read MoreJan. 6, 2022