Hassane Mchaourab
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Apex Lecture presented by renowned AlphaFold founder
The Aug. 30 School of Medicine Basic Sciences Apex Lecture featured visionary biophysicist John Jumper (BS’07). His talk described AlphaFold, the revolutionary protein structure-predicting program, that he co-developed. Read MoreSep. 13, 2023
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John Jumper, developer of AlphaFold, to present an Apex Lecture on August 30
John Jumper, Ph.D. To highlight major inflection points in research, the Vanderbilt School of Medicine Basic Sciences launched the Apex Lecture Series earlier this year, which allows the Basic Sciences community to engage with researchers from around the world who are influencing the trajectory of their fields. John… Read MoreAug. 8, 2023
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Vanderbilt launches Center for Applied Artificial Intelligence in Protein Dynamics
Vanderbilt University School of Medicine Basic Sciences has launched the Center for Applied Artificial Intelligence in Protein Dynamics, which is focused on the intersection of artificial intelligence, machine learning and macromolecular mechanism. It will be led by Hassane Mchaourab, who holds the Louise B. McGavock Chair… Read MoreApr. 12, 2023
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Collaborative research yields new protein structure
Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read MoreMay. 16, 2022
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First-time isolation of Glucose-6-phosphatase leads to novel discoveries
Researchers from the labs of Hassane Mchaourab and Richard O’Brien, both professors of molecular physiology and biophysics, have successfully isolated active glucose-6-phosphatase (G6Pase) and characterized its biophysical and biochemical properties. G6Pase dysfunction is a primary contributor to metabolic diseases, including diabetes, and labs have been trying for years to isolate… Read MoreJan. 25, 2022
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Study explores how bacteria become drug resistant
Researchers at Vanderbilt University and the University of Arizona have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs. Their findings, which were reported recently in the journal Nature Chemical Biology, will aid the search for inhibitors… Read MoreJan. 6, 2022