News
Alissa Weaver leads team to study extracellular RNA in colorectal cancer
Apr. 30, 2020—by Leigh MacMillan A multidisciplinary team of investigators at Vanderbilt University and Vanderbilt University Medical Center has received a program project grant from the National Cancer Institute to explore extracellular RNA in colorectal cancer. The five-year, $9 million award will support multiple projects that aim to define fundamental biological principles about extracellular RNA signaling and...
Bill Tansey receives Exton Award for Research Leading to Innovative Biological Concepts
Apr. 30, 2020—Recipient of the JOHN H. EXTON AWARD for Research Leading to Innovative Biological Concepts: William Tansey, PhD, Ingram Professor of Cancer Research and professor of Cell & Developmental Biology and Biochemistry Tansey is being honored for innovative methodological advances and impactful discoveries that have advanced understanding of MYC, a family of proteins overexpressed in cancer....
Awards honor research staff’s crucial contributions
Feb. 22, 2020—Alan Simmons & Sean Schaffer were honored last week for research excellence during the 16th annual Research Staff Awards luncheon at the Kimpton Aertson Hotel in Nashville. Schaffer, an expert in a wide range of microscopy modalities, is an essential part of the CISR and collaborates with researchers across the university and medical center, wrote CISR...
Tansey’s research is highlighted in a new Basic Sciences “discovery” article
Feb. 8, 2020—Cancers are complex and diverse in nature, assailing the human body through different mechanisms. Cancer cells outsmart normal cells through myriad mechanisms, including sustained proliferation, insensitivity to growth suppressors, and resistance to cell death. MYC is a transcription factor (it regulates the expression of other genes) that plays important roles in human development, but it...
Vanderbilt-led team discovers new genetic disease and defines underlying mechanism
Jan. 18, 2020—Jan. 13, 2020, 11:00 AM Cartilage cells in the zebrafish model of the disease CATIFA (right) have reduced volumes and irregular shapes compared to healthy cartilage cells (left) because of a defect in collagen secretion. (image courtesy of Ela Knapik, MD) by Leigh MacMillan Studies that started in zebrafish have now pointed to a role...
2019 PDB Annual Retreat Photo
Sep. 25, 2019—Group photograph of those attending the 2019 PDB Annual Retreat at Pickwick Landing State Park on September 5 & 6, 2019 (enlarge).
Controlling WNT Signaling Through DVL2
Aug. 28, 2019—