Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission
Rasmussen ML , Robertson GL , Gama V , . Cell metabolism. 2020 6 3; 31(6). 1047-1049
- PMID: 32492390 [PubMed].
Mitochondrial fission is sustained through contact with several organelles, including the endoplasmic reticulum, lysosomes, and the actin cytoskeleton. Nagashima et al. (2020) now demonstrate that PI(4)P-containing Golgi-derived vesicles also modulate mitochondrial fission, driven by Arf1 and PI(4)KIIIβ activity, identifying a new organelle contact involved in maintaining mitochondrial homeostasis.
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