Resistance is futile: Centering forces yield for asymmetric cell division
Alper J , Zanic M , . The Journal of cell biology. 2019 3 4; 218(3). 727-728
- PMID: 30770435 [PubMed].
- PMCID: PMC6400559.
Asymmetric cell division relies on microtubule-based forces to asymmetrically position the mitotic apparatus. In this issue, Sallé et al. (2019. https://doi.org/10.1083/jcb.201807102) use magnetic tweezers to induce asymmetric division in sea urchin zygotes, demonstrating that asymmetry could arise from a time-dependent weakening of centering forces.