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Resistance is futile: Centering forces yield for asymmetric cell division

Authors

Alper J Joshua , Zanic M Marija .
The Journal of cell biology. 2019 3 4; 218(3).
727-728

Abstract

Asymmetric cell division relies on microtubule-based forces to asymmetrically position the mitotic apparatus. In this issue, Sallé et al. (2019. https://doi.org/10.1083/jcb.201807102) use magnetic tweezers to induce asymmetric division in sea urchin zygotes, demonstrating that asymmetry could arise from a time-dependent weakening of centering forces.



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