News
Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly
Jan. 23, 2009—Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly ovary keeps the niche young. Insulin reverses the effects of aging and poor diet, at least on cells within the ovaries of fruit flies. Biologists Daniela Drummond-Barbosa and Hwei-Jan Hsu of Vanderbilt University in Nashville, Tennessee, found that boosting levels of...
Understanding the molecular mechanisms of stem cell maintenance
Dec. 30, 2008—Labosky lab establishes a conserved role for the stem cell gene Foxd3 in maintenance of multipotent neural crest progenitor cells in the mouse embryo. Lu Teng1,*,, Nathan A. Mundell2,4,, Audrey Y. Frist3,4, Qiaohong Wang1 and Patricia A. Labosky1,2,3,4, 1 Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6058, USA....
Vice Chancellor for Research
Nov. 21, 2008—Three Vanderbilt University School of Medicine faculty members are taking on new leadership roles. Susan Wente, Ph.D., has been named assistant vice chancellor for Research.
Young Innovator Award
Oct. 6, 2008—NIH Director’s New Innovator Award recipient As part of NIH's commitment to increasing opportunities for new scientists, it has created the NIH Director's New Innovator Award to support exceptionally creative new investigators who propose highly innovative projects that have the potential for unusually high impact. Melanie Ohi recently received the highly competitive National Institutes of...
The Clp1-Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1
Oct. 6, 2008—The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid Cdc14 phosphatases antagonize cyclin-dependent kinase–directed phosphorylation events and are involved in several facets of cell cycle control. We investigate the role of the fission yeast Cdc14 homologue Clp1/Flp1 in cytokinesis. We find that Clp1/Flp1 is tethered at the contractile ring (CR)...