News
P. Ohi lab’s first paper
Feb. 22, 2010—P.Ohi lab’s first paper hit the press today in Current Biology, this issue The Kinesin-8 Kif18A Dampens Microtubule Plus-End Dynamics Yaqing Du1, Chauca A. English1 and Ryoma Ohi 1 Department of Cell and DevelopmentalBiology, Vanderbilt University School of Medicine, 465 21st AvenueSouth, Nashville, TN 37232-8240, USA Received 2 June 2009; revised 1 December 2009; accepted...
Basic Science Leadership Changes
Dec. 29, 2009—Dear Colleagues, As 2009 comes to a close, I would like to take this opportunity to wish you well and to announce these important changes for senior leadership within the departments of Cell and Developmental Biology and Cancer Biology. These changes are effective January 1. First, I would like to address leadership changes within the...
golgi-derived-clasp-dependent-microtubules-control
Sep. 10, 2009—Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells.
Chancellor’s Awards for Research
Sep. 10, 2009—Irina Kaverina and others, recognized with Chancellor’s Awards for Research, which recognizes excellence in research, scholarship or creative expression. Chancellor's Awards Page VUcast faculty assembly
Identifying a borealin component of the yeast chromosome passenger complex
Aug. 26, 2009—Identifying a borealin component of the yeast chromosome passenger complex.
Sonic hedgehog signaling regulates a novel epithelial progenitor
Aug. 25, 2009—Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C. Development. 2009 Aug;136(15):2535-43. Epub 2009 Jul 1. Note that VUMC reporter will do an aliquot report on this paper on August 14 2. Shh and Gli3 activities...
Microvilli give gut vesicles the brush-off
Jul. 31, 2009—A surprising new function for intestinal cells in shaping theirlocal environment.Every cell lining the small intestine bristles with thousandsof tightly packed microvilli that project into the gut lumen,forming a brush border that absorbs nutrients and protects thebody from intestinal bacteria. McConnell et al. now find thatmicrovilli extend their functional reach even further usinga molecular motor...
Chemicals turn human embryonic stem cells towards beta cells
Apr. 7, 2009—nature chemical biology 5, 195 – 196 (2009) doi:10.1038/nchembio0409-195 Yu-Ping Yang1 & Chris Wright1 Yu-Ping Yang and Chris Wright are in the Department of Cell and Developmental Biology and the Vanderbilt University Program in Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. e-mail: chris.wright@vanderbilt.edu Abstract Small-molecule library screening identifies simple imitators of the cellular...
Defining elements in contractile ring assembly
Mar. 27, 2009—Vanderbilt Reporter, Lords of the contractile ring Cell division requires the formation of a contractile ring. While many protein components of this ring are known, how they interact with each other and with the plasma membrane remains unclear. Rachel Roberts-Galbraith, Kathy Gould, Ph.D., and colleagues are studying these ring proteins in yeast. One such protein,...
Membrane Curvature’s Pore Relation
Mar. 20, 2009—ER membrane–bending proteins are necessary for de novo nuclear pore formation T. Renee Dawson1, Michelle D. Lazarus1, Martin W. Hetzer2, and Susan R. Wente1 1 Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232 2 Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037 Correspondence to...
Cells cycle with no poles
Feb. 18, 2009—Cells cycle with no poles- no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila Julie A. Merkle1, Jamie L. Rickmyre1, Aprajita Garg2, Erin B. Loggins1, Jeanne N. Jodoin1, Ethan Lee1, Louisa P. Wu2 and Laura A. Lee1,* 1 Department of Cell and Developmental Biology, Vanderbilt University Medical Center, U-4200...
Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly
Jan. 23, 2009—Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly ovary keeps the niche young. Insulin reverses the effects of aging and poor diet, at least on cells within the ovaries of fruit flies. Biologists Daniela Drummond-Barbosa and Hwei-Jan Hsu of Vanderbilt University in Nashville, Tennessee, found that boosting levels of...
Understanding the molecular mechanisms of stem cell maintenance
Dec. 30, 2008—Labosky lab establishes a conserved role for the stem cell gene Foxd3 in maintenance of multipotent neural crest progenitor cells in the mouse embryo. Lu Teng1,*,, Nathan A. Mundell2,4,, Audrey Y. Frist3,4, Qiaohong Wang1 and Patricia A. Labosky1,2,3,4, 1 Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6058, USA....
Vice Chancellor for Research
Nov. 21, 2008—Three Vanderbilt University School of Medicine faculty members are taking on new leadership roles. Susan Wente, Ph.D., has been named assistant vice chancellor for Research.
Young Innovator Award
Oct. 6, 2008—NIH Director’s New Innovator Award recipient As part of NIH's commitment to increasing opportunities for new scientists, it has created the NIH Director's New Innovator Award to support exceptionally creative new investigators who propose highly innovative projects that have the potential for unusually high impact. Melanie Ohi recently received the highly competitive National Institutes of...