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MSTPublications: March 2020

Mar. 29, 2020—Lipopolysaccharide Induced Opening of the Blood Brain Barrier on Aging 5XFAD Mouse Model. Barton SM, Janve VA, McClure R, Anderson A, Matsubara JA, Gore JC, Pham W. J Alzheimers Dis. 2019;67(2):503-513. doi: 10.3233/JAD-180755. The development of neurotherapeutics for many neurodegenerative diseases has largely been hindered by limited pharmacologic penetration across the blood-brain barrier (BBB). Previous...

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MSTPublications: January 2020

Jan. 30, 2020—Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption. Elsakr JM, Deeter C, Ricciardi V, Gannon M. J Vis Exp. 2019 Dec 18;(154). doi: 10.3791/60696. The measurement of oxygen consumption in spheroid clusters of cells, such as ex vivo pancreatic islets, has historically been challenging. We demonstrate the measurement of islet oxygen consumption using a 96-well...

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MSTPublications: December 2019

Dec. 19, 2019—Specific Molecular Recognition as a Strategy to Delineate Tumor Margin Using Topically Applied Fluorescence Embedded Nanoparticles. Barton S, Li B, Siuta M, Vaibhav J, Song J, Holt CM, Tomono T, Ukawa M, Kumagai H, Tobita E, Wilson K, Sakuma S, Pham W. Precis Nanomed. 2018 Nov 25;1(3):194-207. doi: 10.33218/prnano1(3).181009.1. Epub 2018 Oct 29. The Thomsen-Friedenreich...

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MSTPublications: October 2019

Oct. 29, 2019—Towards Machine Learning Prediction of Deep Brain Stimulation (DBS) Intra-operative Efficacy Maps. Bermudez C, Rodriguez W, Huo Y, Hainline AE, Li R, Shults R, D’Haese PD, Konrad PE, Dawant BM, Landman BA. Proc SPIE Int Soc Opt Eng. 2019 Mar;10949. pii: 1094922. doi: 10.1117/12.2509728. Deep brain stimulation (DBS) has the potential to improve the quality...

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MSTPublications: September 2019

Sep. 27, 2019—The intrinsically disordered region of the cytokinetic F-BAR protein Cdc15 provides a unique essential function in maintenance of cytokinetic ring integrity. Mangione MC, Snider CE, Gould KL. Mol Biol Cell. 2019 Sep 11:mbcE19060314. doi: 10.1091/mbc.E19-06-0314. [Epub ahead of print] Successful separation of two daughter cells (i.e. cytokinesis) is essential for life. Many eukaryotic cells divide...

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MSTPublications: August 2019

Aug. 27, 2019—Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer. Dudzinski SO, Cameron BD, Wang J, Rathmell JC, Giorgio TD, Kirschner AN. J Immunother Cancer. 2019 Aug 14;7(1):218. doi: 10.1186/s40425-019-0704-z. Background: Prostate cancer is poorly responsive to immune checkpoint inhibition, yet a combination with radiotherapy may enhance...

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MSTPublications: July 2019

Jul. 30, 2019—Anatomical context improves deep learning on the brain age estimation task. Bermudez C, Plassard AJ, Chaganti S, Huo Y, Aboud KE, Cutting LE, Resnick SM, Landman BA. Magn Reson Imaging. 2019 Jun 24. pii: S0730-725X(18)30609-X. doi: 10.1016/j.mri.2019.06.018. [Epub ahead of print] Deep learning has shown remarkable improvements in the analysis of medical images without the...

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MSTPublications: June 2019

Jun. 25, 2019—p73 regulates epidermal wound healing and induced keratinocyte programming. Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA. PLoS One. 2019 Jun 19;14(6):e0218458. doi: 10.1371/journal.pone.0218458. eCollection 2019. p63 is a transcriptional regulator of ectodermal development that is required for basal cell...

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MSTPublications: May 2019

May. 30, 2019—Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors. DiCarlo GE, Aguilar JI, Matthies HJ, Harrison FE, Bundschuh KE, West A, Hashemi P, Herborg F, Rickhag M, Chen H, Gether U, Wallace MT, Galli A. J Clin Invest. 2019 May 16;130. pii: 127411. doi: 10.1172/JCI127411. The precise regulation of synaptic dopamine (DA) content...

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MSTPublications: April 2019

Apr. 29, 2019—Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli. Beebout CJ, Eberly AR, Werby SH, Reasoner SA, Brannon JR, De S, Fitzgerald MJ, Huggins MM, Clayton DB, Cegelski L, Hadjifrangiskou M. MBio. 2019 Apr 2;10(2). pii: e02400-18. doi: 10.1128/mBio.02400-18. Biofilms are multicellular bacterial communities encased in a self-secreted extracellular matrix comprised of...

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