New Publications
MSTPublications: April 2024
Apr. 29, 2024—Solid organ transplant recipients exhibit more TET2-mutant clonal hematopoiesis of indeterminate potential not driven by increased transplantation risk. Silver AJ, Vlasschaert C, Mack T, Sharber B, Xu Y, Bick AG, Pinson CW, Savona MR. Clin Cancer Res. 2024 Mar 29. doi: 10.1158/1078-0432.CCR-23-3840. Online ahead of print. Purpose: Solid organ transplant recipients comprise a unique population...
MSTPublications: March 2024
Mar. 29, 2024—Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation. Yan C, Grabowska ME, Dickson AL, Li B, Wen Z, Roden DM, Michael Stein C, Embí PJ, Peterson JF, Feng Q, Malin BA, Wei WQ. NPJ Digit Med. 2024 Feb 26;7(1):46. doi: 10.1038/s41746-024-01038-3. Drug repurposing represents an attractive alternative to...
MSTPublications: February 2024
Feb. 29, 2024—Relative predictive value of sociodemographic factors for chronic diseases among All of Us participants: a descriptive analysis. Kunnath AJ, Sack DE, Wilkins CH. BMC Public Health. 2024 Feb 8;24(1):405. doi: 10.1186/s12889-024-17834-1. Background: Although sociodemographic characteristics are associated with health disparities, the relative predictive value of different social and demographic factors remains largely unknown. This study...
MSTPublications: January 2024
Jan. 30, 2024—Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Brown BP, Stein RA, Meiler J, Mchaourab HS. J Chem Theory Comput. 2024 Jan 12. doi: 10.1021/acs.jctc.3c01081. Online ahead of print. Protein thermodynamics is intimately tied to biological function and can enable processes such as signal transduction, enzyme catalysis, and molecular recognition. The...
MSTPublications: December 2023
Dec. 18, 2023—Developing and evaluating pediatric phecodes (Peds-Phecodes) for high-throughput phenotyping using electronic health records. Grabowska ME, Van Driest SL, Robinson JR, Patrick AE, Guardo C, Gangireddy S, Ong HH, Feng Q, Carroll R, Kannankeril PJ, Wei WQ. J Am Med Inform Assoc. 2023 Dec 1:ocad233. doi: 10.1093/jamia/ocad233. Online ahead of print. Objective: Pediatric patients have different...
MSTPublications: November 2023
Nov. 29, 2023—Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of raptor and this contributes to the weight loss effect of liraglutide. Le TDV, Liu D, Besing GK, Raghavan R, Ellis BJ, Ceddia RP, Collins S, Ayala JE. Elife. 2023 Nov 6;12:e80944. doi: 10.7554/eLife.80944. Online ahead of print. The canonical target of the glucagon-like peptide-1 receptor (GLP-1R), Protein...
MSTPublications: October 2023
Oct. 31, 2023—Spatiospectral image processing workflow considerations for advanced MR spectroscopy of the brain. Cai LY, Del Tufo SN, Barquero L, D’Archangel M, Sachs L, Cutting LE, Glaser N, Ghetti S, Jaser SS, Anderson AW, Jordan LC, Landman BA. bioRxiv. 2023 Sep 12:2023.09.07.556701. doi: 10.1101/2023.09.07.556701. Preprint. PMID: 37745381 Magnetic resonance spectroscopy (MRS) is one of the few non-invasive...
MSTPublications: September 2023
Sep. 28, 2023—Artificial Intelligence to Preoperatively Predict Proximal Junction Kyphosis Following Adult Spinal Deformity Surgery: Soft Tissue Imaging May be Necessary for Accurate Models. Johnson GW, Chanbour H, Ali MA, Chen J, Metcalf T, Doss D, Younus I, Jonzzon S, Roth SG, Abtahi AM, Stephens BF, Zuckerman SL. Spine (Phila Pa 1976). 2023 Aug 30. doi: 10.1097/BRS.0000000000004816....
MSTPublications: August 2023
Aug. 30, 2023—Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI. Doss DJ, Johnson GW, Narasimhan S, Shless JS, Jiang JW, González HFJ, Paulo DL, Lucas A, Davis KA, Chang C, Morgan VL, Constantinidis C, Dawant BM, Englot DJ. AJNR Am J Neuroradiol. 2023 Aug 10. doi: 10.3174/ajnr.A7950. Online ahead of print. Background and...
MSTPublications: July 2023
Jul. 30, 2023—Unified tumor growth mechanisms from multimodel inference and dataset integration. Beik SP, Harris LA, Kochen MA, Sage J, Quaranta V, Lopez CF. PLoS Comput Biol. 2023 Jul 5;19(7):e1011215. doi: 10.1371/journal.pcbi.1011215. eCollection 2023 Jul. Mechanistic models of biological processes can explain observed phenomena and predict responses to a perturbation. A mathematical model is typically constructed using...