New Publications
MSTPublications: January 2024
Jan. 30, 2024—Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Brown BP, Stein RA, Meiler J, Mchaourab HS. J Chem Theory Comput. 2024 Jan 12. doi: 10.1021/acs.jctc.3c01081. Online ahead of print. Protein thermodynamics is intimately tied to biological function and can enable processes such as signal transduction, enzyme catalysis, and molecular recognition. The...
MSTPublications: December 2023
Dec. 18, 2023—Developing and evaluating pediatric phecodes (Peds-Phecodes) for high-throughput phenotyping using electronic health records. Grabowska ME, Van Driest SL, Robinson JR, Patrick AE, Guardo C, Gangireddy S, Ong HH, Feng Q, Carroll R, Kannankeril PJ, Wei WQ. J Am Med Inform Assoc. 2023 Dec 1:ocad233. doi: 10.1093/jamia/ocad233. Online ahead of print. Objective: Pediatric patients have different...
MSTPublications: November 2023
Nov. 29, 2023—Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of raptor and this contributes to the weight loss effect of liraglutide. Le TDV, Liu D, Besing GK, Raghavan R, Ellis BJ, Ceddia RP, Collins S, Ayala JE. Elife. 2023 Nov 6;12:e80944. doi: 10.7554/eLife.80944. Online ahead of print. The canonical target of the glucagon-like peptide-1 receptor (GLP-1R), Protein...
MSTPublications: October 2023
Oct. 31, 2023—Spatiospectral image processing workflow considerations for advanced MR spectroscopy of the brain. Cai LY, Del Tufo SN, Barquero L, D’Archangel M, Sachs L, Cutting LE, Glaser N, Ghetti S, Jaser SS, Anderson AW, Jordan LC, Landman BA. bioRxiv. 2023 Sep 12:2023.09.07.556701. doi: 10.1101/2023.09.07.556701. Preprint. PMID: 37745381 Magnetic resonance spectroscopy (MRS) is one of the few non-invasive...
MSTPublications: September 2023
Sep. 28, 2023—Artificial Intelligence to Preoperatively Predict Proximal Junction Kyphosis Following Adult Spinal Deformity Surgery: Soft Tissue Imaging May be Necessary for Accurate Models. Johnson GW, Chanbour H, Ali MA, Chen J, Metcalf T, Doss D, Younus I, Jonzzon S, Roth SG, Abtahi AM, Stephens BF, Zuckerman SL. Spine (Phila Pa 1976). 2023 Aug 30. doi: 10.1097/BRS.0000000000004816....
MSTPublications: August 2023
Aug. 30, 2023—Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI. Doss DJ, Johnson GW, Narasimhan S, Shless JS, Jiang JW, González HFJ, Paulo DL, Lucas A, Davis KA, Chang C, Morgan VL, Constantinidis C, Dawant BM, Englot DJ. AJNR Am J Neuroradiol. 2023 Aug 10. doi: 10.3174/ajnr.A7950. Online ahead of print. Background and...
MSTPublications: July 2023
Jul. 30, 2023—Unified tumor growth mechanisms from multimodel inference and dataset integration. Beik SP, Harris LA, Kochen MA, Sage J, Quaranta V, Lopez CF. PLoS Comput Biol. 2023 Jul 5;19(7):e1011215. doi: 10.1371/journal.pcbi.1011215. eCollection 2023 Jul. Mechanistic models of biological processes can explain observed phenomena and predict responses to a perturbation. A mathematical model is typically constructed using...
New Publications: June 2023
Jun. 26, 2023—Exploratory Multisite Magnetic Resonance Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children. Cai LY, Tanase C, Anderson AW, Patel NJ, Lee CA, Jones RS, LeStourgeon LM, Mahon A, Taki I, Juvera J, Pruthi S, Gwal K, Ozturk A, Kang H, Rewers A, Rewers MJ, Alonso GT, Glaser...
MSTPublications: May 2023
May. 30, 2023—A Representativeness-informed Model for Research Record Selection from Electronic Medical Record Systems. Borza VA, Clayton EW, Kantarcioglu M, Vorobeychik Y, Malin BA. AMIA Annu Symp Proc. 2023 Apr 29;2022:259-268. eCollection 2022. Scientific and clinical studies have a long history of bias in recruitment of underprivileged and minority populations. This underrepresentation leads to inaccurate, inapplicable, and...
MSTPublications: April 2023
Apr. 26, 2023—Microfluidic Platforms Promote Polarization of Human-Derived Retinal Ganglion Cells That Model Axonopathy. Boal AM, McGrady NR, Chamling X, Kagitapalli BS, Zack DJ, Calkins DJ, Risner ML. Transl Vis Sci Technol. 2023 Apr 3;12(4):1. doi: 10.1167/tvst.12.4.1. Purpose: Axons depend on long-range transport of proteins and organelles which increases susceptibility to metabolic stress in disease. The axon...