New Publications
MSTPublications: April 2021
Apr. 30, 2021—Cytochrome bd promotes Escherichia coli biofilm antibiotic tolerance by regulating accumulation of noxious chemicals. Beebout CJ, Sominsky LA, Eberly AR, Van Horn GT, Hadjifrangiskou M. NPJ Biofilms Microbiomes. 2021 Apr 16;7(1):35. doi: 10.1038/s41522-021-00210-x. Nutrient gradients in biofilms cause bacteria to organize into metabolically versatile communities capable of withstanding threats from external agents including bacteriophages, phagocytes,...
MSTPublications: March 2021
Mar. 30, 2021—Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting. Du Z*, Brown BP*, Kim S, Ferguson D, Pavlick DC, Jayakumaran G, Benayed R, Gallant JN, Zhang YK, Yan Y, Red-Brewer M, Ali SM, Schrock AB, Zehir A, Ladanyi M, Smith AW, Meiler J, Lovly CM....
MSTPublications: February 2021
Feb. 24, 2021—General Purpose Structure-Based Drug Discovery Neural Network Score Functions with Human-Interpretable Pharmacophore Maps. Brown BP, Mendenhall J, Geanes AR, Meiler J. J Chem Inf Model. 2021 Jan 26. doi: 10.1021/acs.jcim.0c01001. Online ahead of print. The BioChemical Library (BCL) is an academic open-source cheminformatics toolkit comprising ligand-based virtual high-throughput screening (vHTS) tools such as quantitative structure-activity/property...
MSTPublications: January 2021
Jan. 28, 2021—Generalizing deep whole-brain segmentation for post-contrast MRI with transfer learning. Bermudez C, Remedios SW, Ramadass K, McHugo M, Heckers S, Huo Y, Landman BA. J Med Imaging (Bellingham). 2020 Nov;7(6):064004. doi: 10.1117/1.JMI.7.6.064004. Epub 2020 Dec 23. PMID: 33381612 Purpose: Generalizability is an important problem in deep neural networks, especially with variability of data acquisition in...
MSTPublications: December 2020
Dec. 18, 2020—Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Ford CA, Spoonmore TJ, Gupta MK, Duvall CL, Guelcher SA, Cassat JE. J Orthop Res. 2020 Dec 10. doi: 10.1002/jor.24948. Online ahead of print. Osteomyelitis is a debilitating infection of bone that results in substantial morbidity. Staphylococcus aureus is the most commonly isolated pathogen...
MSTPublications: November 2020
Nov. 23, 2020—Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19. Lofgren SM, Nicol MR, Bangdiwala AS, Pastick KA, Okafor EC, Skipper CP, Pullen MF, Engen NW, Abassi M, Williams DA, Nascene AA, Axelrod ML, Lother SA, MacKenzie LJ, Drobot G, Marten N, Cheng MP, Zarychanski R, Schwartz IS, Silverman M, Chagla Z, Kelly LE, McDonald...
MSTPublications: October 2020
Oct. 29, 2020—Association between measured teamwork and medical errors: an observational study of prehospital care in the USA. Herzberg S, Hansen M, Schoonover A, Skarica B, McNulty J, Harrod T, Snowden JM, Lambert W, Guise JM. BMJ Open. 2019 Oct 31;9(10):e025314. doi: 10.1136/bmjopen-2018-025314. Objectives: The goal of this study was to examine the relationship between measured teamwork...
MSTPublications: September 2020
Sep. 28, 2020—Reconstruction of Upper Third Ear Defects: Utility of a Limited Tanzer Reduction. Colazo JM, Farinas AF, Leonhard V, Valmadrid A, Kaoutzanis C, Thayer WP. World J Plast Surg. 2020 May;9(2):179-185. doi: 10.29252/wjps.9.2.179. PMID: 32934930 Background: Large ear defects (>3 cm) present a significant reconstructive challenge and often require extensive operations, which can lead to donor-site...
MSTPublications: August 2020
Aug. 26, 2020—Changes in peripheral and local tumor immunity after neoadjuvant chemotherapy reshape clinical outcomes in patients with breast cancer. Axelrod ML, Nixon MJ, Gonzalez-Ericsson PI, Bergman RE, Pilkinton MA, McDonnell WJ, Sanchez V, Opalenik S, Loi S, Zhou J, Mackay S, Rexer BN, Abramson VG, Jansen VM, Mallal SA, Donaldson J, Tolaney SM, Krop I, Garrido-Castro...
MSTPublications: July 2020
Jul. 28, 2020—Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci. LaBella AL*, Abraham A*, Pichkar Y, Fong SL, Zhang G, Muglia LJ, Abbot P, Rokas A, Capra JA. Nat Commun. 2020 Jul 24;11(1):3731. doi: 10.1038/s41467-020-17258-6. PMID: 32709900 Currently, there is no comprehensive framework to evaluate the evolutionary forces acting on...