New Publications
MSTPublications: June 2020
Jun. 25, 2020—DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons. Klofas LK, Short BP, Snow JP, Sinnaeve J, Rushing GV, Westlake G, Weinstein W, Ihrie RA, Ess KC, Carson RP. Neurobiol Dis. 2020 Jun 20:104975. doi: 10.1016/j.nbd.2020.104975. [Epub ahead of print] Mutations in the DEPDC5 gene can cause epilepsy, including forms...
MSTPublications: May 2020
May. 20, 2020—Cerebrospinal fluid biomarkers of neurodegeneration, synaptic dysfunction, and axonal injury relate to atrophy in structural brain regions specific to Alzheimer’s disease. Moore EE, Gifford KA, Khan OA, Liu D, Pechman KR, Acosta LMY, Bell SP, Turchan M, Landman BA, Blennow K, Zetterberg H, Hohman TJ, Jefferson AL. Alzheimers Dement. 2020 May 6. doi: 10.1002/alz.12087. [Epub...
MSTPublications: April 2020
Apr. 29, 2020—Expanding cultural and ancestral representation in psychiatric genetic studies. Kang J, Ruderfer DM. Neuropsychopharmacology. 2020 Apr 15. doi: 10.1038/s41386-020-0676-1. [Epub ahead of print] No abstract available. Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1. Klofas LK, Short BP, Zhou C, Carson RP....
MSTPublications: January 2020
Jan. 30, 2020—Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption. Elsakr JM, Deeter C, Ricciardi V, Gannon M. J Vis Exp. 2019 Dec 18;(154). doi: 10.3791/60696. The measurement of oxygen consumption in spheroid clusters of cells, such as ex vivo pancreatic islets, has historically been challenging. We demonstrate the measurement of islet oxygen consumption using a 96-well...
MSTPublications: December 2019
Dec. 19, 2019—Specific Molecular Recognition as a Strategy to Delineate Tumor Margin Using Topically Applied Fluorescence Embedded Nanoparticles. Barton S, Li B, Siuta M, Vaibhav J, Song J, Holt CM, Tomono T, Ukawa M, Kumagai H, Tobita E, Wilson K, Sakuma S, Pham W. Precis Nanomed. 2018 Nov 25;1(3):194-207. doi: 10.33218/prnano1(3).181009.1. Epub 2018 Oct 29. The Thomsen-Friedenreich...
MSTPublications: October 2019
Oct. 29, 2019—Towards Machine Learning Prediction of Deep Brain Stimulation (DBS) Intra-operative Efficacy Maps. Bermudez C, Rodriguez W, Huo Y, Hainline AE, Li R, Shults R, D’Haese PD, Konrad PE, Dawant BM, Landman BA. Proc SPIE Int Soc Opt Eng. 2019 Mar;10949. pii: 1094922. doi: 10.1117/12.2509728. Deep brain stimulation (DBS) has the potential to improve the quality...
MSTPublications: July 2019
Jul. 30, 2019—Anatomical context improves deep learning on the brain age estimation task. Bermudez C, Plassard AJ, Chaganti S, Huo Y, Aboud KE, Cutting LE, Resnick SM, Landman BA. Magn Reson Imaging. 2019 Jun 24. pii: S0730-725X(18)30609-X. doi: 10.1016/j.mri.2019.06.018. [Epub ahead of print] Deep learning has shown remarkable improvements in the analysis of medical images without the...
MSTPublications: May 2019
May. 30, 2019—Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors. DiCarlo GE, Aguilar JI, Matthies HJ, Harrison FE, Bundschuh KE, West A, Hashemi P, Herborg F, Rickhag M, Chen H, Gether U, Wallace MT, Galli A. J Clin Invest. 2019 May 16;130. pii: 127411. doi: 10.1172/JCI127411. The precise regulation of synaptic dopamine (DA) content...
MSTPublications: April 2019
Apr. 29, 2019—Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli. Beebout CJ, Eberly AR, Werby SH, Reasoner SA, Brannon JR, De S, Fitzgerald MJ, Huggins MM, Clayton DB, Cegelski L, Hadjifrangiskou M. MBio. 2019 Apr 2;10(2). pii: e02400-18. doi: 10.1128/mBio.02400-18. Biofilms are multicellular bacterial communities encased in a self-secreted extracellular matrix comprised of...
MSTPublications: March 2019
Mar. 28, 2019—J-N Gallant’s recent first-author paper was featured here in the VUMC Reporter! Katherine Konvinse’s recent first-author paper was featured here in the VUMC Reporter! Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration. Colazo JM, Evans BC, Farinas AF, Al-Kassis S, Duvall C, Thayer WP. Tissue Eng Part B Rev. 2019 Mar 21. doi:...