New Publications
MSTPublications: November 2020
Nov. 23, 2020—Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19. Lofgren SM, Nicol MR, Bangdiwala AS, Pastick KA, Okafor EC, Skipper CP, Pullen MF, Engen NW, Abassi M, Williams DA, Nascene AA, Axelrod ML, Lother SA, MacKenzie LJ, Drobot G, Marten N, Cheng MP, Zarychanski R, Schwartz IS, Silverman M, Chagla Z, Kelly LE, McDonald...
MSTPublications: October 2020
Oct. 29, 2020—Association between measured teamwork and medical errors: an observational study of prehospital care in the USA. Herzberg S, Hansen M, Schoonover A, Skarica B, McNulty J, Harrod T, Snowden JM, Lambert W, Guise JM. BMJ Open. 2019 Oct 31;9(10):e025314. doi: 10.1136/bmjopen-2018-025314. Objectives: The goal of this study was to examine the relationship between measured teamwork...
MSTPublications: September 2020
Sep. 28, 2020—Reconstruction of Upper Third Ear Defects: Utility of a Limited Tanzer Reduction. Colazo JM, Farinas AF, Leonhard V, Valmadrid A, Kaoutzanis C, Thayer WP. World J Plast Surg. 2020 May;9(2):179-185. doi: 10.29252/wjps.9.2.179. PMID: 32934930 Background: Large ear defects (>3 cm) present a significant reconstructive challenge and often require extensive operations, which can lead to donor-site...
MSTPublications: August 2020
Aug. 26, 2020—Changes in peripheral and local tumor immunity after neoadjuvant chemotherapy reshape clinical outcomes in patients with breast cancer. Axelrod ML, Nixon MJ, Gonzalez-Ericsson PI, Bergman RE, Pilkinton MA, McDonnell WJ, Sanchez V, Opalenik S, Loi S, Zhou J, Mackay S, Rexer BN, Abramson VG, Jansen VM, Mallal SA, Donaldson J, Tolaney SM, Krop I, Garrido-Castro...
MSTPublications: July 2020
Jul. 28, 2020—Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci. LaBella AL*, Abraham A*, Pichkar Y, Fong SL, Zhang G, Muglia LJ, Abbot P, Rokas A, Capra JA. Nat Commun. 2020 Jul 24;11(1):3731. doi: 10.1038/s41467-020-17258-6. PMID: 32709900 Currently, there is no comprehensive framework to evaluate the evolutionary forces acting on...
MSTPublications: June 2020
Jun. 25, 2020—DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons. Klofas LK, Short BP, Snow JP, Sinnaeve J, Rushing GV, Westlake G, Weinstein W, Ihrie RA, Ess KC, Carson RP. Neurobiol Dis. 2020 Jun 20:104975. doi: 10.1016/j.nbd.2020.104975. [Epub ahead of print] Mutations in the DEPDC5 gene can cause epilepsy, including forms...
MSTPublications: May 2020
May. 20, 2020—Cerebrospinal fluid biomarkers of neurodegeneration, synaptic dysfunction, and axonal injury relate to atrophy in structural brain regions specific to Alzheimer’s disease. Moore EE, Gifford KA, Khan OA, Liu D, Pechman KR, Acosta LMY, Bell SP, Turchan M, Landman BA, Blennow K, Zetterberg H, Hohman TJ, Jefferson AL. Alzheimers Dement. 2020 May 6. doi: 10.1002/alz.12087. [Epub...
MSTPublications: April 2020
Apr. 29, 2020—Expanding cultural and ancestral representation in psychiatric genetic studies. Kang J, Ruderfer DM. Neuropsychopharmacology. 2020 Apr 15. doi: 10.1038/s41386-020-0676-1. [Epub ahead of print] No abstract available. Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1. Klofas LK, Short BP, Zhou C, Carson RP....
MSTPublications: March 2020
Mar. 29, 2020—Lipopolysaccharide Induced Opening of the Blood Brain Barrier on Aging 5XFAD Mouse Model. Barton SM, Janve VA, McClure R, Anderson A, Matsubara JA, Gore JC, Pham W. J Alzheimers Dis. 2019;67(2):503-513. doi: 10.3233/JAD-180755. The development of neurotherapeutics for many neurodegenerative diseases has largely been hindered by limited pharmacologic penetration across the blood-brain barrier (BBB). Previous...
MSTPublications: January 2020
Jan. 30, 2020—Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption. Elsakr JM, Deeter C, Ricciardi V, Gannon M. J Vis Exp. 2019 Dec 18;(154). doi: 10.3791/60696. The measurement of oxygen consumption in spheroid clusters of cells, such as ex vivo pancreatic islets, has historically been challenging. We demonstrate the measurement of islet oxygen consumption using a 96-well...