Job Opportunity: Postdoctoral/Biologist Position, Immune Regulation Unit, NIDCR, NIH, Bethesda, MD
POSITION DESCRIPTION:
A Biologist/post doctoral position is available in the Tussiwand laboratory. This position can potentially translate to a staff scientist position. We are studying the development of immune subsets at steady state and in the context of disease. Our Lab is committed to understand how development of immune subsets occurs and how ontogeny translates into specific functions. The transcriptional identity is shared across multiple immune subsets where specific modules of interactions and TF networks define on one hand their development and on the other hand their functional properties. Understanding the basic principles that govern theses networks and modules is instrumental to understand immune related pathologies and harness the immune system. Our research combines in vivo (e.g. mouse genetics, experimental models of infection and tumors, adoptive cell transfers), in vitro (e.g. cellular immunology, flow cytometry, Crispr-mediated mutagenesis, human samples related research, and computational approaches.
More information at https://irp.nih.gov/pi/roxane-tussiwand
The applicant is expected to – help with general Lab maintenance – maintain a research project, – contribute to research conducted by other scientists within and outside of the laboratory, – provide initial training to incoming students.
Qualifications:
The ideal candidate will show creative and flexible thinking and will work semi-independently to investigate new and evolving questions and to establish and optimize new or cutting-edge experimental approaches. The position requires strong analytical skills, updated knowledge of the scientific literature, and ability to collaborate with colleagues and trainees with different scientific expertise and objectives. The successful candidate will be expected to present communications at multi-laboratory group meetings or scientific conferences and to prepare scientific papers. Applicants should have an established record of publications that provides evidence of their scientific accomplishments and expertise. The work is mostly laboratory-based and requires a flexible schedule to accommodate experiment needs.
Specific requirements:
§ MS or PhD or equivalent doctoral degree in immunology, biochemistry, genetics or a similar field, with experience in immunology-related research.
§ documented expertise and experience related to the laboratory research and objectives, specifically in the following areas:
§ conventional molecular biology techniques (e.g. plasmid DNA cloning, western blotting)
§ Genetic engineering (including retroviral transduction and Crispr-Cas9 mutagenesis).
§ flow cytometry, including instrument trouble-shooting and operation of cell sorters.
§ in vitro cellular immunology techniques (i.e analyses of T cell proliferation, B cell activation, cytokine expression,
§ expertise in in vivo mouse models, including adoptive cell transfer, Single cell preparation form tissues and bone marrow chimera procedures.
§ experimental models of mouse infections, including LCMV, and of mouse tumors are a plus.
§ experience in animal colony management.
§ Basic or advanced computational skills for analyses of gene expression and sequencing, including experimental procedures and bioinformatics analyses.
To Apply:
Please submit applications to Roxane Tussiwand, roxane.tussiwand@nih.gov. Applications should include a cover letter, a short (one page) statement of accomplishments and research interests addressing the qualification requirements listed above, and a Curriculum Vitae, with a list of publications. Salary is commensurate with experience.
This position is subject to a background investigation.
The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.