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Department of Biochemistry

Primary Investigator Track Faculty

Primary Faculty

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Manuel Ascano, Jr., Ph.D.

Associate Professor, Biochemistry
Associate Professor, Pathology, Microbiology & Immunology
Dean Faculty Fellow

DNA/RNA detection & regulation in innate immunity & viral pathogenesis

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Rahul Bhowmick , Ph.D.

Assistant Professor , Biochemistry

DNA replication stress and genome instability

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Breann Brown, Ph.D.

Assistant Professor, Biochemistry

Structural biology & protein assembly

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Bruce D. Carter, Ph.D.

Professor , Biochemistry
Natalie Overall Warren Chair in Biochemistry
Associate Director, Vanderbilt Brain Institute

Neurotrophin signaling, glia-mediated phagocytosis & Schwann cell biology

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Walter J. Chazin, Ph.D.

Chancellor's Chair in Medicine
Senior Associate Dean, Biomedical Research Education & Training (BRET)
Professor of Biochemistry & Chemistry
Director, Molecular Biophysics Training Program

Structural cell biology

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David K. Cortez, Ph.D.

Chair of Biochemistry Department
Richard N. Armstrong Ph.D. Chair for Innovation in Biochemistry
Professor of Biochemistry
Associate Director for Basic Science Research at Vanderbilt-Ingram Cancer Center

Genome maintenance by the DNA damage response

Cortez Lab Website

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James M. Dewar, Ph.D.

Assistant Professor of Biochemistry

Termination of DNA synthesis, DNA replication & repair

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Martin Egli, Ph.D.

Professor of Biochemistry

Structural biology of circadian clocks, nucleic acids & DNA polymerases

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Stephen W. Fesik, Ph.D.

Professor of Biochemistry & Pharmacology & Chemistry
Orrin H. Ingram II Chair in Cancer Research
Tadashi Inagami Chair in Biochemistry

Fragment and structure based drug discovery

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Andrew Folkmann, Ph.D.

Assistant Professor, Biochemistry

Molecular mechanics of cellular compartmentalization

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F. Peter Guengerich, Ph.D.

Professor of Biochemistry
Tadashi Inagami Chair in Biochemistry

Chemistry/enzymology of bioactivation & detoxication of foreign compounds

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Scott W. Hiebert, Ph.D.

Professor of Biochemistry
Associate Professor of Medicine
Hortense B. Ingram Chair in Cancer Research

Oncogenic transcription factors, chemical-genetics, nascent transcription, genomics, proteomics

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Emily Hodges, Ph.D.

Associate Professor, Biochemistry
Member, Vanderbilt Genetics Institute
Chancellor's Faculty Fellow

Epigenetics, gene regulation

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Katrin Karbstein , Ph.D.

Ingram Professor of Cancer Research
Professor , Biochemistry
Co-Leader, Cancer Cell Biology Program, Vanderbilt-Ingram Cancer Center (VICC)

Ribosome homeostasis via ribosome assembly and repair

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Douglas Kojetin, Ph.D.

Associate Professor, Biochemistry
Associate Professor, Center for Structural Biology
Associate Professor, Vanderbilt Institute of Chemical Biology
Director of Graduate Studies for Biochemistry

Structural biology and molecular pharmacology of nuclear receptor transcription factors

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John Kuriyan, Ph.D.

Dean, School of Medicine Basic Sciences
Vanderbilt University School of Medicine
Mary Geddes Stahlman Chair
University Distinguished Professor of Biochemistry,
Chemistry, and Cell and Developmental Biology

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Lawrence J. Marnett, Ph.D.

Dean Emeritus, Basic Sciences, Vanderbilt University School of Medicine
University Distinguished Professor
Mary Geddes Stahlman Professor of Cancer Research
University Professor of Biochemistry and Chemistry
Professor of Pharmacology

Oxidative lipid metabolism in inflammation & cancer

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Houra Merrikh, Ph.D.

Professor, Biochemistry, PMI, VI4

DNA Replication, mutagenesis, & evolution

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Sezen Meydan , Ph.D.

Assistant Professor , Biochemistry

Cellular surveillance by ribosomes & neuronal translation & translation-related diseases

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Douglas A. Mitchell

Professor, Biochemistry and Chemistry
William Kelly Warren Sr. Chair in Biochemistry
Director, Vanderbilt Institute for Chemical Biology

chemical biology, natural product biosynthesis, enzyme engineering, synthetic biology

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Neil Osheroff, Ph.D.

Professor of Biochemistry
Professor of Medicine (Hematology/Oncology)
John G. Coniglio Chair in Biochemistry
Past-Director, Academy for Excellence in Education
Co-Leader, Foundations of Medical Knowledge Phase

Topoisomerase function and the mechanism of anticancer & antibacterial agents

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Jennifer A. Pietenpol, Ph.D.

Professor of Biochemistry
Ingram Professor of Cancer Research
Brock Family Directorship in Career Development
Executive Vice President for Research
Chief Scientific and Strategy Officer
Vanderbilt University Medical Center

Triple negative breast cancer & p53 family proteins

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Yi Ren, Ph.D.

Associate Professor of Biochemistry

Structural biology of mRNA nuclear export & viral exploitation

https://lab.vanderbilt.edu/ren-lab

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Charles R. Sanders, Ph.D.

Professor of Biochemistry & Medicine
Senior Advisor to the Dean of Basic Sciences
Aileen M. Lange & Annie Mary Lyle Chair, Cardiovascular Research

 Chemical and structural biology of membrane proteins

Mechanisms and drug discovery for Charcot-Marie-Tooth disease and long QT syndrome

 

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Kevin L. Schey, Ph.D.

Professor, Biochemistry, Ophthalmology & Visual Sciences
Stevenson Chair in Biochemistry
Director of Core Facilities, Mass Spectrometry Research Center

Proteomics analysis in development and disease; mass spectrometry technology development

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Will Wan, Ph.D.

Assistant Professor, Biochemistry
Member, Vanderbilt Center for Structural Biology

Structural biology in near-native states, viral structure & assembly