Senior Research Scientist, StemSynergy Therapeutics, Inc., Nashville TN
Senior Research Scientist at StemSynergy Therapeutics, Inc.
Job description
StemSynergy Therapeutics, Inc has an opportunity for a Senior Research Scientist to join our laboratory in Nashville, TN. This position is focused on medicinal chemistry in the area of cancer drug discovery.
Job Responsibilities:
· The successful candidate will plan and execute multistep synthetic pathways compatible with rapid analog development of small molecules for discovery and lead optimization.
· Work effectively in collaboration with team members in the areas of molecular and cellular biology, pharmacology, molecular informatics, ADME, structural biology, chemical development, and other key functions.
· Assist with the analysis of screening data, perform literature reviews, design, propose, and execute all medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies; Supervise and direct synthetic chemistry activities at contract research organizations (CROs) or internally; safely conduct multi-step synthetic organic reactions under the guidance of the director of medicinal chemistry.
· Laboratory responsibilities include set-up of reaction apparatus, addition of reagents and solvents, monitoring reactions, work-up, separation, purification (recrystallization, distillation, chromatography, etc.) and analysis (NMR, IR, melting-point, etc.).
· Other tasks include general oversight and maintenance/organization of the laboratory.
Job Qualifications:
· Applicants should possess superior intellectual ability, a strong record of previous accomplishments, hold a Ph.D in organic or medicinal chemistry or a MSc degree with appropriate experience.
· Experience with LCMS/HPLC (especially Agilent systems) is preferred.
· Candidate must have 5+ years laboratory experience in the synthesis, purification and characterization of organic compounds.
· Knowledge of ChemOffice and SciFinder are required.
· Experience with computer aided drug design is preferred
· Candidates must have excellent verbal and written communication skills.
· US citizenship or permanent residency required.
· English must be your first language.
· Experience in writing grant applications preferred
For more information and to apply: https://goo.gl/Kcy8Hm