Job Opportunity: Senior Associate Scientist, GTx Upstream Development, Pfizer, Morrisville, NC
Interested in this job? We have an alumni contact. Email kate.stuart@vanderbilt.edu for more info.
ROLE SUMMARY
The Gene Therapy area of the Bioprocess R&D department is responsible for the development of GMP manufacturing processes for our gene therapy products. The Senior Associate Scientist in Upstream process development is responsible for designing and executing mammalian cell bioreactor experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes.
ROLE RESPONSIBILITIES
The Senior Associate Scientist will have experience in laboratory research, and a desire to continue in a laboratory-focused role. The successful candidate will be responsible for working with fellow scientists to develop robust, efficient, scalable strategies for improving upstream process performance. Responsibilities will include conducting experiments and tests as part of a variety of research and development activities, e.g., small-scale studies, pilot plant and manufacturing upstream studies. The Senior Associate Scientist will be expected to summarize and evaluate the study results and to design and test new hypotheses to improve the fundamental understanding of upstream cell culture processes.
Specific Roles
• Design and execute mammalian cell culture experiments
• Utilize shake flasks, single use bioreactors and bench top stirred tank bioreactors for cell growth.
• Perform analytical methods to monitor cell growth, metabolites, and analyze productivity of cultures.
• Prepare samples for analysis for both internal and external shipment to outside laboratories
• Communicate experimental results both orally and in written reports
• Record complete and accurate laboratory data in accordance Pfizer’s policies. Adheres to Pfizer’s safety work processes
QUALIFICATIONS
Required: Bachelor’s Degree with 2+ years of experience, or MS degree with 0+ years of experience, degree in biological science or chemical/biological engineering
• Prior cell culture experience in a laboratory setting, preferably in process development of biotherapeutics
• Basic skills include aseptic technique, cell counting, culturing mammalian cell lines in shake flasks and/or bioreactors, thawing and freezing cell lines, and determination of cell culture metabolites
• Willing to expand scientific skills and accept direction from senior staff members. Ability to learn new procedures and work with computerized process control equipment
• Ability to execute detailed experimental plans, record procedures, and analyze data
• Self-motivated, organized, capable of working independently and in a collaborative environment.
• Able to work in a fast-paced team environment with changing priorities
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.