Job Posting: Research Fellowship, COVID-19 pathogenesis and innate response to adjuvanted vaccines, FDA/Center for Biologics Evaluation and Research, Silver Springs, MD
Position Type
A research fellowship position on Viral Pathogenesis and Immunobiology is available in the Laboratory of Retrovirus Research, CBER, FDA at the White Oak Campus in Silver Spring, Maryland.
Position Description
- The postdoc will investigate the mechanisms of inflammatory response in severe COVID-19 disease. Severe COVID disease is associated with dysregulated immune responses as evidenced by the presence of high levels of inflammatory markers including IL-6, TNF-a, IL-6 cytokines, and C-reactive protein that together represent a so-called cytokine storm, a complication that is observed in majority of patients with severe illness. The ongoing research involves study of the potential of Immunoglobulin (Ig) Immune Complexes formed by anti-SARS CoV-2 antibodies to enhance production of PGE2 and of inflammatory cytokines by innate cells and their contribution to cytokine storm. The information gained in this research helps address safety of IgG treatments for COVID-19.
- Additional projects include study of the safety of mucosal vaccines in the surrogate model of lung epithelial tissue is being developed in the laboratory. This system provides a unique tool to use multiple techniques including flow cytometry, confocal microscopy and molecular biology techniques to identify critical pathways responsible for innate responses in the lung epithelial tissue with the focus on mucosal vaccine safety.
- Our laboratory provides a dynamic and vibrant community where fellows investigate immune response to several respiratory pathogens including SARS-CoV2, RSV, and influenza and study various aspects of immune response to vaccines. A highly collaborative biomedical research environment prioritizes mentoring and training and provides with opportunity to lead their own projects, present their research internally and externally, and publish in top scientific journals.
- This is a training fellowship for two years with possible extension up to 5 years.
Qualifications:
- Highly motivated candidates should be within 3 years of their PhD degree. Candidates with research experience in biochemistry, cell biology, and protein chemistry are encouraged to apply.
Eligibility
- This position is only open for US citizens, permanent residents (Green Card holders) or individuals residing in US for at least 3 years in past 5 years on a valid US visa.
Salary
- Candidates will be offered a competitive salary depending on their experience.
How to Apply:
- Interested applicants should send curriculum vitae, bibliography, together with list of three of reference by email to:
Hana Golding, Ph. D. E-mail: Hana.Golding@fda.hhs.gov
Marina Zaitseva Ph. D E-mail: Marina.Zaitseva