Job Opportunity: Molecular Biology Research Scientist, Assay Development, Verici Dx, Franklin, TN
Molecular Biology Research Scientist, Assay Development
Verici Dx pairs leading edge laboratory science with artificial intelligence to create innovative clinical tools. We have validated multiple leading-edge prognostic tests and continue to innovate to develop a complementary suite of tests forming an organ transplant platform for personalized patient and organ response risk to assist clinicians in medical management for improved patient outcomes.
The Company also has a mission to accelerate the pace of innovation by supporting research using the fully characterized data from the underlying technology and in collaboration with medical device, biopharmaceutical and data science partners. We are singularly focused on providing insights that inform the path to overall graft survival and successful outcomes for patients.
We are seeking a skilled scientist in molecular biology, transcriptomics and proteomics to define and perform laboratory procedures and data analysis for development of an array of next generation sequencing-based in vitro diagnostic tests. The ideal candidate will be proficient in advanced transcriptomic and proteomic techniques such as isolation of extracellular vesicles, nucleic acid extraction, library preparation, pcr, QC, and next gen sequencing. The incumbent will collaborate with other scientists to plan, design, and execute experimental studies, analyse, write reports/summaries, and communicate results from these studies, and engage in effective decision-making process.
Duties and Responsibilities:
- Support strategic planning and documentation for the design and development of novel and innovative laboratory clinical tests in solid organ transplant and related fields.
- Develop protocols for specimen processing and analysis and organize experimental plans to be performed adhering to defined timelines.
- Conduct analysis of blood, urine, or tissue to determine expression levels of genes and profiles of proteins of interest.
- Perform quality controls during experimental procedures according to protocols and report deviations and observations.
- Analyze experimental results using statistical tools.
- Review test results, maintain legible work records, document findings in reports, prepare and present summaries of data and findings.
- Participate in meetings internally and with external stakeholders.
- Collaborate cross functionally with clinical and data science experts and associates to ensure team success.
- Contribute to scientific presentations and manuscripts preparation.
- Perform routine laboratory tasks, such as biorepository storage organization and record keeping, instrument maintenance and basic calibration, ordering of reagents and supplies.
- Abide by laboratory safety policies and procedures.
Requirements and Education:
At a minimum, the successful candidate will hold a MSc or equivalent, PhD preferred, in one of the biological sciences and one of the following at a minimum: four years of related experience or completion of a molecular training program with at least two years of experience in a molecular laboratory.
Important Skills:
- Detail-oriented and thorough.
- Excellent organizational skills, including the ability to efficiently evaluate, prioritize, and handle multiple and changing projects and priorities.
- Technical writing skills to document results, produce reports, and other documents. Ability to analyze experimental results using statistical tools, interpret and summarize experimental results in a clear, concise, and accurate manner.
- Dependability, following instructions, responding to management direction, completing tasks in a timely manner or notifying appropriate persons with an alternate plan as needed.
- Ability to deal with frequent changes, or unexpected events, and timelines
- Ability to work with limited supervision as well as in a collaborative team setting.
- Strong interpersonal skills that foster a positive environment.
- Excellent verbal and written communication skills in the English language.
- Computer skills including proficiency with Microsoft Office applications.
- High-standards in best laboratory practices while working in a biohazard laboratory environment.
- Exercise good judgment when determining what actions to take when trouble-shooting assays or equipment and in root cause analysis.
Experience:
Required
- Experience in nucleic acid extraction, quantification and QC, polymerase chain reaction, and next generation sequencing in fluid (i.e. blood, urine etc) and tissue specimens.
- Experience in evaluating sequencing data using various commercial software applications in the context of both RNA quality and alignment with an understanding of the disease process and or question under interrogation.
- Experience in isolation and QC of extracellular vesicles
- Experience in assisting bioinformatic sequencing analysis by preparing sequencing data.
- Experience in handling, organizing, and processing of human specimens.
- Experience in sterile techniques and prevention of cross contamination.
- Good Laboratory Practice and Good Clinical Practice.
Desired
- Experience in automation laboratory instrumentation
- Experience in operating cloud-based genomic data analysis tools, such as Illumina BaseSpace
- Experience developing SOPs and related documents for compliance in a regulated environment
- Experience in working in a CLIA-certified laboratory
- Experience contributing to or writing manuscripts for scientific literature.
US: 393 Nichol Mill Lane, Suite 200, Franklin, TN 37067
UK: Avon House, 19 Stanwell Road, Penarth, Cardiff, CF64 2EZ